December 8, 2003

Neurochem's Annual General and Special Shareholders' meeting and media briefing session.

- Neurochem, Inc. (NASDAQ: NRMX, TSX: NRM) - Dr. Francesco Bellini, Chairman and Chief Executive Officer of Neurochem Inc., invites the news media to the Annual General and Special Shareholders' Meeting that will be held on Tuesday, December 9, 2003, at 10:00 A.M., in the Sarah Bernhardt Ballroom of the InterContinental Montreal Hotel, 360 St-Antoine St. West, in Montreal.

Immediately following the shareholders' meeting, a media briefing will be held in the Vieux-Montréal room. Dr. Bellini and other company spokespeople will be available to discuss the Company's strategy for the coming year.

Date Book

What
Annual General and Special Shareholders' Meeting and Media Briefing

Who
Dr. Francesco Bellini, Chairman of the Board and Chief Executive Officer, Neurochem Inc.

When
Tuesday, December 9, 2003
10:00 A.M. Sarah Bernhardt Ballroom (annual meeting)
11:00 A.M. Vieux-Montréal room (media briefing)

Where
InterContinental Montreal Hotel, 360 St-Antoine St. West, Montreal

For Information
Roch Landriault
(514) 843-2345

About Neurochem

Neurochem is focused on the development and commercialization of innovative therapeutics for neurological disorders. The Company's staged pipeline of proprietary, disease-modifying, oral products addresses critical unmet medical needs. Fibrillex™, designated an orphan drug, is in a Phase II/III clinical trial for AA amyloidosis. Alzhemed™ has completed a Phase II clinical trial. Cerebril™ is in a Phase II trial for the prevention of hemorrhagic stroke caused by cerebral amyloid angiopathy. Neurochem is also developing a product for the potential treatment of epileptic seizures induced by traumatic brain injury. For additional information on Neurochem, please visit our website at: (www.neurochem.com).

Certain statements contained in this news release, other than statements of fact that are independently verifiable at the date hereof, may constitute forward-looking statements. Such statements, based as they are on the current expectations of management, inherently involve numerous risks and uncertainties, known and unknown, many of which are beyond Neurochem's control. Such risks include but are not limited to: the impact of general economic conditions, general conditions in the pharmaceutical industry, changes in the regulatory environment in the jurisdictions in which Neurochem does business, stock market volatility, fluctuations in costs, and changes to the competitive environment due to consolidation as well as other risks included in public filings of Neurochem. Consequently, actual future results may differ materially from the anticipated results expressed in the forward-looking statements. The reader should not place undue reliance on the forward-looking statements included in this news release.

These statements speak only as of the date made and Neurochem is under no obligation and disavows any intention to update or revise such statements as a result of any event, circumstances or otherwise.

For further Information, please contact:
Dr. Lise Hébert
Vice President, Corporate Communications
lhebert@neurochem.com

275 Armand-Frappier
Laval (Quebec)
H7V 4A7
Tel: (450) 680-4500
Fax: (450) 680-4501

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