November 9, 2001

U.S. patent issued for Neurochem.

New Patent for Epilepsy Program Expands on Company's Central Nervous System (CNS) Platform


Neurochem Inc. (TSX : NRM) announces the issuance of a patent in the U.S. No. 6,306,909 relating to the Company's Epilepsy program. The U.S. patent was issued to Neurochem's research collaborators in the field of Epilepsy at Queen's University.

"The addition of this patent further strengthens our CNS intellectual property portfolio," said Dr. Louis R. Lamontagne, President and CEO of Neurochem. "The U.S. patent issued in this area gives us a solid base for further investigation of our innovative Epilepsy research platform. Queen's University was recently awarded a grant totalling $398,600 for its research program with Neurochem from the Natural Sciences and Engineering Research Council (NSERC)," he added.

Neurochem's novel Epilepsy program aims at introducing a new class of drugs. Accordingly, the Company is focusing on the development of an innovative treatment with the objective of not only blocking seizures and convulsions associated with the disease, but also of preventing the progression of the disease. The dual-action lead drug candidates identified by the Company are expected to act both as an anti-convulsant - to prevent seizures, as well as an anti-epileptogenic - to prevent the genesis and progression of the disease iTSXlf. The issued patent covers methods and compounds useful for the inhibition or prevention of convulsive disorders, including epilepsy. Lead candidates have been identified and are currently undergoing toxicity studies.

About Epilepsy

Epilepsy is a neurological disorder characterized by seizures involving a loss of normal movement, disrupted consciousness and convulsions. It is a devastating condition, which is complicated by the multiplicity of its causal factors. Worldwide there is an estimated 45 million patients suffering from Epilepsy. Neurochem has identified a large unmet clinical need for new therapeutic options for Epilepsy that offer both a cure for the disease and relief of the symptoms.

About Neurochem

Neurochem is an industry leader in the development of therapeutic drugs and diagnostic tools for central nervous system and amyloid-related diseases associated with aging. The Company has built a strong product pipeline by developing a novel, proprietary series of compounds that inhibit the formation, deposition and toxic effects of amyloid fibrils within the body. Neurochem's therapeutic programs target Alzheimer's Disease, Epilepsy, Systemic Amyloidosis, Diabetes Type II and Hemorrhagic Stroke (due to Cerebral Amyloid Angiopathy). Neurochem is using a multi-pronged approach towards the development of pharmaceuticals for Alzheimer's Disease, including glycosaminoglycans (GAGs) mimetics, a vaccine, an anti-inflammatory and neuroprotective approaches as well as the creation of a diagnostic imaging tool. The Company has advanced to date three drug candidates to clinical trials: Alzhemed™, for the treatment of Alzheimer's Disease, Fibrillex™, for the orphan disease Secondary Amyloidosis, and Cerebril™, for Hemorrhagic Stroke. At present, the Company employs over 70 people and is located in Saint-Laurent, Canada (www.neurochem.com).

All of the statements contained in this news release, other than statements of fact which are independently verifiable at the date hereof, are forward-looking statements. Such statements, based as they are on the current expectations of management, inherently involve numerous risks and uncertainties, known and unknown. Some examples of known risks are: the impact of general economic conditions, general conditions in the pharmaceutical industry, changes in the regulatory environment in the jurisdictions in which Neurochem does business, stock market volatility, fluctuations in costs, and changes to the competitive environment due to consolidation or otherwise. Consequently, actual future results may differ materially from the anticipated results expressed in the forward-looking statements.

For further Information, please contact:
Dr. Lise Hébert
Vice President, Corporate Communications
lhebert@neurochem.com

275 Armand-Frappier
Laval (Quebec)
H7V 4A7
Tel: (450) 680-4500
Fax: (450) 680-4501

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